![The Rule of Five Revisited: Applying Log D in Place of Log P in Drug-Likeness Filters | Molecular Pharmaceutics The Rule of Five Revisited: Applying Log D in Place of Log P in Drug-Likeness Filters | Molecular Pharmaceutics](https://pubs.acs.org/cms/10.1021/mp0700209/asset/images/large/mp0700209h00001.jpeg)
The Rule of Five Revisited: Applying Log D in Place of Log P in Drug-Likeness Filters | Molecular Pharmaceutics
![SOLVED: N i. Calculate the Log-P values of the following drugs: (2 marks) Are these compounds hydrophilic or lipophilic? (1 mark) NHz 13 OH HO Cefaclor Ibuprofen SOLVED: N i. Calculate the Log-P values of the following drugs: (2 marks) Are these compounds hydrophilic or lipophilic? (1 mark) NHz 13 OH HO Cefaclor Ibuprofen](https://cdn.numerade.com/ask_images/e9dc79c1837d49c1a891817b1e5e9794.jpg)
SOLVED: N i. Calculate the Log-P values of the following drugs: (2 marks) Are these compounds hydrophilic or lipophilic? (1 mark) NHz 13 OH HO Cefaclor Ibuprofen
![Water-solvent partition coefficients and Delta Log P values as predictors for blood-brain distribution; application of the Akaike information criterion. | Semantic Scholar Water-solvent partition coefficients and Delta Log P values as predictors for blood-brain distribution; application of the Akaike information criterion. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/a2efbfd39513228b99bfa1cde5fd891bc79a7afa/6-Table4-1.png)
Water-solvent partition coefficients and Delta Log P values as predictors for blood-brain distribution; application of the Akaike information criterion. | Semantic Scholar
![SOLVED: .13. Calculate the theoretical log P value for (c) The log P for benzene is 2 of the substituents to the structure below. Suggest a change to one make the molecule SOLVED: .13. Calculate the theoretical log P value for (c) The log P for benzene is 2 of the substituents to the structure below. Suggest a change to one make the molecule](https://cdn.numerade.com/ask_images/0a376697c5334e889f41f63a7fe54474.jpg)